Can you believe that Marisa Tomei is 52? I sure as hell can't, because she doesn't even remotely look it. I think it's safe to say that she'll go down as the hottest Aunt May in all of Spider-Man's cinematic adventures. While we got a taste of what to expect from her interpretation of the character in Captain America: Civil War, I'd be hard pressed to argue that most fanboys aren't hoping for more of her in Spider-Man: Homecoming.
Sure there are probably some out there who don't care what Aunt May is up to, but there is a precedent in the Spider-Man movies for the character to have a subplot. Sure it's usually the most boring and uninteresting part of any Spider-Man movie, but Aunt May's never been a stone cold fox before—no offense to Sally Field or Rosemary Harris. Odds are whatever her role in the film entails, it will likely involve Tony Stark dropping by and trying to get in her pants.
While the film is not called Spider-Man: Aunt May's Big, Sexy Adventure, with Marisa Tomei officially taking on the role for the foreseeable future, I wouldn't mind working a film with that title into the franchise. I think it would be a welcome addition to the Marvel Cinematic Universe.